Preemptive use of oral gabapentin or pregabalin for acute postoperative pain following lower limb orthopaedic surgery under spinal anaesthesia Acharya U, Ghimire A, Bhattarai B, Singh SN, Prasad JN, Maharjan R

Abstract: Background: Postoperative pain is a major cause of perioperative morbidity and functional impairment. Preemptive analgesia is an analgesia regimen instituted before the surgery, to desensitize the pain pathways. Pregabalin and gabapentin have been claimed to be effective in reducing postoperative pain without significant alterations in hemodynamics.   Objectives: This study was conducted Read more…