Abstract
Introduction: About 70% of cervical cancer occurrences globally are caused by Human Papilloma Virus strains 16 and 18. The prevalence of cervical cancer can be decreased by Human papilloma virus vaccines that protect against Human papilloma virus 16 and 18 infections. The World Health Organization had identified vaccine hesitancy as one of the top 10 threats to global health in 2019. A study conducted in China shows that 62.36% medical students reported having Human papilloma virus vaccine hesitancy.
Objectives: To assess the Human papilloma virus vaccine hesitancy among female undergraduate students in a medical college of Kathmandu, Nepal.
Methodology: A descriptive cross-sectional study was conducted among 428 female undergraduate students studying at a Medical College, Kathmandu. Data was collected by self-administered questionnaire using google form and analyzed by using Statistical Package for Social Science version 27.
Results: Out of 428 respondents, 377 (88.1%) had Human papilloma vaccination hesitancy. Convenience was pointed out as the major domain with highest hesitancy against the Human Papilloma vaccine. Among all the reasons, the expensive cost of Human Papilloma vaccine was the main reasons for respondent's hesitancy against Human Papilloma vaccine.
Conclusion: The findings of the study showed very high hesitancy regarding Human papilloma virus vaccine. Educating students about the advantages of the Human Papilloma vaccine and making it more affordable will help lower vaccine hesitancy and increase Human Papilloma vaccine vaccination rates, eventually reduce the prevalence of cervical cancer.
References
Kombe Kombe AJ, Li B, Zahid A, Mengist HM, Bounda GA, Zhou Y, et al. Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation. Front Public Health. 2021;8(January):1–19. [FullText | DOI]
ICO. Human Papillomavirus and Related Diseases Report. 2016;(October). [Link]
Braaten KP, Laufer MR. Human Papillomavirus (HPV), HPV-Related Disease, and the HPV Vaccine. Review in Obstetrics and Gynecology. 2008;1(1):2–10. [PubMed]
WHO. Ten threats to global health in 2019. [Accessed September 14, 2023]. [Link]
Zhang E, Dai Z, Wang S, Wang X, Zhang X, Fang Q. Vaccine Literacy and Vaccination: A Systematic Review. Int J Public Health. 2023;68(February):1–7. [PubMed]
MacDonald NE, Eskola J, Liang X, Chaudhuri M, Dube E, Gellin B, et al. Vaccine hesitancy: Definition, scope and determinants. Vaccine. 2015;33(34):4161–4. [FullText | DOI]
Huang Y, Chen C, Wang L, Wu H, Chen T, Zhang L. HPV Vaccine Hesitancy and Influencing Factors among University Students in China: A Cross- Sectional Survey Based on the 3Cs Model. Int J Environ Res Public Health. 2022;19(21). [FullText | DOI]
Zhou L, Wang J, Cheng P, Li Y, Liu G, Zhang X. HPV Vaccine Hesitancy Among Medical Students in China: A Multicenter Survey. Front Public Health. 2022;10(February):1–8. [FullText | DOI]
Singh Y, Shah A, Singh M, Verma S, Shrestha BM, Vaidya P, Nakarmi RP, Shrestha SB. Human papilloma virus vaccination in Nepal: an initial experience in Nepal. Asian Pac J Cancer Prev. 2010;11(3):615-7. [PubMed]
Machida M, Inoue S. Patterns of HPV vaccine hesitancy among catch-up generations in Japan: A descriptive study. Vaccine. 2023 May 2;41(18):2956–60. [FullText | DOI]
Alsanafi M, Salim NA, Sallam M. Willingness to get HPV vaccination among female university students in Kuwait and its relation to vaccine conspiracy beliefs. 2023;19(1):1–10. [FullText | DOI]
The Kathmandu Post. Post Report, December 16, 2024. Available from: [Link]
