Eosinophilic pleural effusion in an eleven-year-old boy


Pleural effusion

How to Cite

Shakya, K. N. ., Shrestha , . A. ., Yadav , A. ., Gautam , U. ., Panday , R. K. ., & Lamichhane , M. . (2021). Eosinophilic pleural effusion in an eleven-year-old boy. Journal of Kathmandu Medical College, 10(2), 95–97. Retrieved from https://jkmc.com.np/ojs3/index.php/journal/article/view/1058


Pleural effusion fluid with ?10% eosinophils may be seen in 5-16% of exudative pleural effusions. Its association with helminthic infestation is reported in the literature. This patient with left-sided eosinophilic pleural effusion was a referred case from another hospital and treated initially as parapneumonic. With inadequate response to antibiotics and a markedly high IgE level praziquantel was started. This resulted in rapid disappearance of symptoms, decrease in the eosinophil count, and radiological improvement. After exclusion of parapneumonic, tuberculosis, autoimmune disease, and malignancy, a trial of antihelminthics should be considered an option. This may spare unnecessary investigations.



Adelman M, Albelda SM, Gottlieb J, Haponik EF. Diagnostic utility of pleural fluid eosinophilia. Am J Med. 1984;77:915-20. [PubMed | Full Text | DOI]

Kalomenidis I, Light RW. Eosinophilic pleural effusions. Curr Opin Pulm Med. 2003;9(4):254-60. [PubMed | Full Text | DOI]

Efrati O, Barak A. Pleural effusions in the paediatric population. Pediatr Rev. 2002;23(12):417-25. [PubMed | Full Text]

Miao R, Zhu Y, Wang Z, Luo S, Wan C. Distinguishment of parasite-infected children from paediatric inpatients with both eosinophilia and effusion. Medicine (Baltimore). 2020;99(14):e19625. [PubMed | Full Text | DOI]

Luo W, Zeng Y, Shen P, He J, Wang J. Diagnostic procedure for idiopathic eosinophilic pleural effusion: A single-center experience. BMC Pulm Med. 2020 Apr 3;20(1):82. [PubMed | Full Text | DOI]

Salaria M, Parmar V, Kochar S, Mehta S. Eosinophilia, pleural effusion, and cysticercosis - Unknown association? Indian Pediatr. 2001 Jun;38(6):671-4. [PubMed | Full Text]

Singh U, Garg N, Chopra V. Eosinophilic pleural effusion and giardiasis: A causal or a casual relationship? Lung India. 2013; 30(1): 69-71. [PubMed | Full Text | DOI]

Okafor NC, Oso AA, Oranu AC, Wolff SM, Murray JJ. Eosinophilic pleural effusion: A rare manifestation of hypereosinophilic syndrome. Case Rep Med. 2009;2009:635309. [PubMed | Full Text | DOI]

Wang J, Luo W, Shen P, He J, Zeng Y. Retrospective study of pleural parasitic infestations: A practical diagnostic approach. BMC Infect Dis. 2019 Jul 4;19(1):576. [PubMed | Full Text | DOI]

Light RW, MacGregor MI, Luchsinger PC, Ball Jr WC. Pleural effusions: The diagnostic separation of transudates and exudates. Ann Intern Med. 1972 Oct;77(4):507-13. [PubMed | Full Text | DOI]